Selank
CAS: 129954-34-3
Category: Peptides
| Purity | Pharmaceutical Grade (≥98%, as per manufacturer specifications), Research Grade ≥97%, Analytical Ref |
| Molecular Formula | C₃₃H₅₇N₁₁O₉ |
| Molecular Weight | 727.87 |
| Appearance | White to off-white lyophilized powder |
| Packaging | 1mg/5mg/10mg/20mg/vial (for research); 0.15% or 0.3% ophthalmic/nasal solution in 3mL glass vials or dropper bottles; 25kg/fiber drum (for bulk pharmaceutical ingredient) |
| Testing Indicators | Appearance — Visual inspection; Identification — HPLC-MS or MALDI-TOF; Purity — HPLC (C18 column, UV detection at 214–220 nm); Peptide content — Amino acid analysis or UV spectrophotometry; Acetate content (counterion) — Ion chromatography; Water content — Karl Fischer titration; Residual solvents — GC; Microbial limits — Plate count method; Endotoxins — LAL test; Mass verification — Mass spectrometry; Sequence verification — Edman degradation or MS/MS; pH (1% solution) — Potentiometry. |
| Storage Notes | Stored as a lyophilized powder at 2–8°C (refrigerated) for short-term or -20°C for long-term; reconstituted solutions should be stored at 2–8°C and used within 24–48 hours; protected from light, moisture, and repeated freeze-thaw cycles; away from strong oxidizers, proteases, and heat sources. |
| Lead Time | days |
Used as an anxiolytic (anti-anxiety) and nootropic peptide; acts as a synthetic analog of human tuftsin (Thr-Lys-Pro-Arg) with an extended C-terminal sequence (Pro-Gly-Pro); exhibits anxiolytic, antidepressant, neuroprotective, and immunomodulatory activities; modulates serotonin, dopamine, and GABAergic neurotransmission; used in research and clinical settings for generalized anxiety disorder, cognitive impairment, ischemic stroke, and hepatitis; primarily administered intranasally; also studied for its ability to enhance learning and memory while reducing stress responses.