Semax
CAS: 80714-61-0
Category: Peptides
| Purity | Pharmaceutical Grade (≥98%, as per manufacturer specifications), Research Grade ≥97%, Analytical Ref |
| Molecular Formula | C₃₇H₅₁N₉O₁₀ |
| Molecular Weight | 781.85 |
| Appearance | White to off-white lyophilized powder or crystalline powder |
| Packaging | 1mg/5mg/10mg/20mg/vial (for research and pharmaceutical use); 0.1% or 1% ophthalmic/nasal solution in 3mL glass vials or dropper bottles; 25kg/fiber drum (for bulk pharmaceutical ingredient) |
| Testing Indicators | Appearance — Visual inspection; Identification — HPLC-MS or MALDI-TOF; Purity — HPLC (C18 column, UV detection at 214–220 nm); Peptide content — Amino acid analysis or UV spectrophotometry; Water content — Karl Fischer titration; Acetate content (counterion) — Ion chromatography; Residual solvents — GC; Microbial limits — Plate count method; Endotoxins — LAL test; Bacterial endotoxins — Kinetic chromogenic assay; Mass verification — Mass spectrometry; Sequence verification — Edman degradation or MS/MS. |
| Storage Notes | Stored as a lyophilized powder at 2–8°C (refrigerated) for short-term or -20°C for long-term; reconstituted solutions should be stored at 2–8°C and used within 24–48 hours; protected from light, moisture, and repeated freeze-thaw cycles; away from strong oxidizers and heat sources. |
| Lead Time | days |
Used as a nootropic and neuroprotective peptide; acts as a synthetic analog of ACTH(4-10) (adrenocorticotropic hormone fragment); used in the treatment of cognitive impairment, ischemic stroke, optic nerve disorders, and attention deficit disorders; exhibits neurotrophic, neuroprotective, and antioxidant activities; modulates brain-derived neurotrophic factor (BDNF) expression; primarily administered intranasally; used in research on neurodegenerative diseases, cognitive enhancement, and stroke recovery.