Enasidenib
CAS: 1446502-11-9
Category: Pharmaceutical Intermediates
| Purity | Research Grade ≥98%, High-Purity Grade ≥99%, Pharmaceutical Grade ≥99.5% |
| Molecular Formula | C19H17F6N7O |
| Molecular Weight | 473.38 |
| Appearance | white to off-white crystalline powder |
| Packaging | 1 g/amber glass vial, 5 g/plastic bottle. |
| Testing Indicators | Appearance — Visual inspection; Identification — IR, Chiral HPLC; Purity — RP-HPLC; Enantiomeric purity — Chiral HPLC; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Filtration; IDH2 inhibitor impurities — LC-MS. |
| Storage Notes | Stored at -20°C in a tightly closed container under inert atmosphere, away from light, moisture, and heat. |
| Lead Time | days |
Used as an IDH2 inhibitor intermediate in the synthesis of oral targeted therapies for relapsed/refractory acute myeloid leukemia with IDH2 mutations.