3-(4-Methylimidazol-1-yl)-5-(trifluoromethyl)aniline hydrochloride
CAS: 917391-26-5
Category: Pharmaceutical Intermediates
| Purity | Research Grade ≥98%; Pharmaceutical Intermediate Grade ≥99%; High-Purity Grade ≥99.5% |
| Molecular Formula | C11H12ClF3N4 |
| Molecular Weight | 276.69 |
| Appearance | White to off-white crystalline powder or solid |
| Packaging | 100 g, 500 g, 1 kg aluminum foil bags; 5 kg or 25 kg fiber drums with inner polyethylene bags; customized pharmaceutical packaging available |
| Testing Indicators | Appearance — Visual inspection; Identification — FTIR spectroscopy and 1H NMR/13C NMR; Purity — HPLC-UV analysis; Assay — HPLC area normalization; Hydrochloride content — Ion chromatography or titration; Residual solvents — GC analysis (ICH Q3C); Water content — Karl Fischer titration; Elemental impurities — ICP-MS; Molecular weight confirmation — LC-MS. |
| Storage Notes | Store in a cool, dry, and well-ventilated warehouse. Keep container tightly sealed and protected from moisture, heat, and direct sunlight. Avoid contact with strong oxidizing agents, strong acids, and strong bases. Recommended storage under inert atmosphere for long-term preservation. |
| Lead Time | 10 days |
3-(4-Methylimidazol-1-yl)-5-(trifluoromethyl)aniline hydrochloride is an important pharmaceutical intermediate containing an aniline structure, imidazole ring, and trifluoromethyl group. It is mainly used as an intermediate in the synthesis of active pharmaceutical ingredients and research compounds, especially for the preparation of kinase inhibitors, antifungal agents, and other nitrogen-containing heterocyclic pharmaceuticals.