Sacubitril hemicalcium salt
CAS: 1369773-39-6
Category: Pharmaceutical Intermediates
| Purity | Reagent Grade ≥98%, High-Purity Grade ≥99%, Technical Grade ≥95% |
| Molecular Formula | C24H28Ca0.5NO5 |
| Molecular Weight | 430.52 |
| Appearance | White to off-white crystalline powder |
| Packaging | 1g/5g/10g or 25kg/cardboard drum or 1kg/aluminum foil bag |
| Testing Indicators | Appearance — Visual inspection; Identification — IR, Calcium test; Purity — RP-HPLC; Calcium — Flame photometry; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Filtration; Neprilysin inhibitor impurities — LC-MS. |
| Storage Notes | Stored in a cool, dry, and well-ventilated place at -20°C in a tightly closed container, protected from light and moisture, away from incompatible materials, heat, and direct sunlight. |
| Lead Time | days |
Used as a neprilysin (NEP) inhibitor prodrug in the formulation of combination therapies with valsartan for treating chronic heart failure by enhancing natriuretic peptide activity.