Roflumilast

CAS: 162401-32-3

Category: Organic Intermediates

PurityReagent Grade ≥98%, High-Purity Grade ≥99%, Pharmaceutical Grade ≥99.5%
Molecular FormulaC17H14Cl2F2N2O3
Molecular Weight403.21
Appearancewhite to off-white crystalline powder
Packaging1 kg/aluminum foil bag, 10 kg/fiber drum.
Testing IndicatorsAppearance — Visual inspection; Identification — IR, LC-MS; Purity — Gradient RP-HPLC; Polymorphic form — XRPD; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Filtration; PDE4 impurities — SEC.
Storage NotesStored in a cool, dry place at room temperature in a tightly closed container, away from light and strong oxidizing agents.
Lead Time days
Used as a PDE4 inhibitor intermediate in the synthesis of anti-inflammatory drugs for COPD and asthma treatment.