5-Bromo-3,3-dimethyl-1H-pyrrolo[2,3-b]pyridin-2(3H)-one
CAS: 1263280-06-3
Category: Organic Pharmaceutical Intermediates
| Purity | Research Grade ≥95%; High-Purity Grade ≥98%; Pharmaceutical Intermediate Grade ≥99% (supplier depend |
| Molecular Formula | C9H9BrN2O |
| Molecular Weight | 241.09 |
| Appearance | White to off-white crystalline powder or solid |
| Packaging | 1 g, 5 g, 10 g amber glass bottles; 25 g or 100 g aluminum foil bags with double polyethylene liner; bulk quantities packed in sealed moisture-proof containers |
| Testing Indicators | Appearance — Visual inspection; Identification — FTIR spectroscopy and NMR spectroscopy (1H NMR, 13C NMR); Molecular weight confirmation — LC-MS/MS or HR-MS; Purity — HPLC-UV/DAD analysis; Related substances — HPLC impurity profiling; Bromine content — ICP-OES or elemental analysis; Residual solvents — GC analysis according to ICH Q3C guidelines; Moisture — Karl Fischer titration. |
| Storage Notes | Store in a cool, dry, and well-ventilated area. Protect from moisture, heat, and direct sunlight. Keep container tightly sealed when not in use. Store under inert atmosphere for long-term preservation. Avoid contact with strong acids, strong bases, and oxidizing agents. |
| Lead Time | 10 days |
5-Bromo-3,3-dimethyl-1H-pyrrolo[2,3-b]pyridin-2(3H)-one is a brominated pyrrolopyridinone derivative mainly used as an advanced pharmaceutical intermediate and research reagent. It serves as a building block in medicinal chemistry for the synthesis of heterocyclic compounds, kinase-related research molecules, and bioactive pharmaceutical candidates.