Argatroban
CAS: 74863-84-6
Category: Organic Pharmaceutical Intermediates
| Purity | Research/API grade typically ≥98% purity (HPLC), with defined limits for related substances, residua |
| Molecular Formula | C23H36N6O5S |
| Molecular Weight | 508.63 |
| Appearance | White to off-white solid (crystalline or amorphous powder) |
| Packaging | Research scale: 1 mg–100 mg glass vials or small bottles; API/bulk scale: multi-gram to multi-kilogram sealed bottles or drums with moisture and light protection, intended for pharmaceutical and research use |
| Testing Indicators | Appearance — visual inspection (color and form); Assay and related substances — HPLC; Identification — ¹H/¹³C NMR, FTIR, and MS, including HPLC retention versus reference; Water content — Karl Fischer titration; Residual solvents — GC; Specific rotation — polarimetry where specified by quality standards. |
| Storage Notes | Store in a tightly closed container in a cool, dry place (typically 2–8 °C or below) protected from light and moisture. Avoid prolonged exposure to elevated temperature and humidity, and keep away from strong oxidizing agents and incompatible chemicals. For solutions, follow specified stability and storage conditions. |
| Lead Time | 10 days |
Synthetic direct thrombin inhibitor used as a non-heparin anticoagulant and pharmaceutical active/intermediate. Applied clinically (in appropriate dosage forms) for the prevention and treatment of thrombosis, especially in patients with heparin-induced thrombocytopenia (HIT), and used as a research tool in thrombosis and coagulation studies.