(3-Hydroxy-2-methylpropyl)triphenylphosphonium bromide
CAS: 81658-47-1
Category: Pharmaceutical Intermediates
| Purity | Reagent Grade ≥98%, High-Purity Grade ≥99% |
| Molecular Formula | C22H24BrOP |
| Molecular Weight | 399.30 |
| Appearance | White to off-white crystalline powder or solid |
| Packaging | 1 g, 5 g, 25 g, 100 g aluminum foil bags; 500 g or 1 kg sealed bottles; customized packaging available for industrial quantities |
| Testing Indicators | Appearance — Visual inspection; Identification — FTIR spectroscopy, ^1H NMR, ^13C NMR, ^31P NMR; Purity — HPLC-UV or HPLC-MS; Molecular weight confirmation — LC-MS or HRMS; Water content — Karl Fischer titration; Residual solvents — GC according to ICH Q3C guidelines; Elemental composition — CHNS/P elemental analysis; Bromide content — Ion chromatography or titration analysis. |
| Storage Notes | Store in a cool, dry, well-ventilated place. Keep container tightly closed and protected from moisture, heat, and direct sunlight. Avoid contact with strong oxidizing agents and strong bases. Store under inert atmosphere for long-term preservation when possible. |
| Lead Time | 10 days |
Used as an organic synthesis intermediate and phosphonium salt reagent. It is commonly employed as a Wittig reagent precursor after base treatment to generate phosphorus ylides for carbon-carbon bond formation and olefination reactions. Applied in pharmaceutical intermediate synthesis, fine chemical synthesis, and preparation of substituted alkenes and alcohol-containing organic molecules.