4-Iodo-2-isobutylanisole

CAS: 475272-03-8

Category: Organic Intermediates

PurityResearch Grade ≥95%; High-Purity Grade ≥98%; Synthesis Grade ≥99% (GC/HPLC).
Molecular FormulaC11H15IO
Molecular Weight290.14
AppearanceWhite to pale yellow crystalline solid or powder; may appear as off-white solid depending on purity.
Packaging1 g, 5 g, 25 g, 100 g amber glass bottles or aluminum foil bags for research quantities; 500 g, 1 kg or larger quantities packed in moisture-proof polyethylene-lined drums.
Testing IndicatorsAppearance — Visual inspection; Identification — FTIR spectroscopy and 1H NMR/13C NMR; Purity — HPLC-UV or GC-FID analysis; Molecular weight confirmation — LC-MS; Iodine content — ICP-MS or iodometric analysis; Water content — Karl Fischer titration (ASTM E203); Residual solvents — GC-MS according to ICH Q3C guidelines; Melting point — Capillary method.
Storage NotesStore in a cool, dry, and well-ventilated area. Keep container tightly closed and protected from light and moisture. Avoid prolonged exposure to heat, strong acids, strong bases, and oxidizing agents. Recommended storage temperature is 2-8°C for long-term stability when available.
Lead Time10 days
4-Iodo-2-isobutylanisole is an iodinated aromatic ether intermediate used as a building block in organic synthesis. It is mainly applied in the preparation of pharmaceutical intermediates, agrochemical intermediates, functional aromatic compounds, and specialty chemicals through cross-coupling reactions such as Suzuki, Heck, and other palladium-catalyzed transformations.