Irinotecan

CAS: 97682-44-5

Category: Alkaloids

PurityReagent Grade ≥98%, High-Purity Grade ≥99%, Technical Grade ≥95%
Molecular FormulaC33H38N4O6
Molecular Weight586.68
AppearanceWhite to pale yellow crystalline powder
Packaging1 g/lyophilized vial, 5 g/amber glass bottle.
Testing IndicatorsAppearance — Visual inspection; Identification — IR, LC-MS; Purity — RP-HPLC; Polymorphic form — XRPD; Residual solvents — HS-GC; Heavy metals — ICP-MS; Moisture — Karl Fischer titration; Microbial limits — Pour plate; Camptothecin impurities — HPLC.
Storage NotesStored as lyophilized powder at 2-8°C in a tightly closed container, protected from light; reconstituted solutions must be used within 24 hours.
Lead Time days
Used as a topoisomerase I inhibitor intermediate in the synthesis of intravenous chemotherapeutic agents for metastatic colorectal cancer.