Ethanol, 2-[4-[(tetrahydro-2H-pyran-2-yl)oxy]phenoxy]-

CAS: 777084-12-5

Category: Organic Intermediates

PurityResearch Grade ≥95%; High-Purity Grade ≥98%; Pharmaceutical Intermediate Grade ≥99%
Molecular FormulaC13H18O4
Molecular Weight238.28
AppearanceColorless to pale yellow liquid or solid (depending on purity and temperature); typically supplied as a clear organic intermediate.
Packaging1 g, 5 g, 25 g, 100 g aluminum foil bags or amber glass bottles for laboratory grade; 25 kg fiber drums or polyethylene-lined drums for industrial quantities.
Testing IndicatorsAppearance — Visual inspection; Identification — FTIR spectroscopy and 1H NMR spectroscopy; Purity — HPLC-UV or GC analysis; Water content — Karl Fischer titration (ASTM E203); Residual solvents — GC-MS or GC-FID according to ICH Q3C guidelines; Molecular structure confirmation — LC-MS; Melting point — Capillary method (for solid samples); Assay — HPLC area normalization method.
Storage NotesStore in a cool, dry, and well-ventilated area. Keep container tightly closed and protected from moisture, heat, and direct sunlight. Avoid contact with strong acids, strong bases, and oxidizing agents. Store under inert atmosphere for long-term storage when possible.
Lead Time10 days
Used as an organic synthesis intermediate. It contains a protected phenoxyethanol structure with a tetrahydropyranyl (THP) protecting group and is commonly used in pharmaceutical intermediate synthesis, especially in the preparation of aromatic ether compounds and bioactive molecules. The THP protecting group can be removed under acidic conditions to generate corresponding phenoxyethanol derivatives.