1-Bromo-3,5-difluorobenzene
CAS: 461-96-1
Category: Organic Intermediates
| Purity | Chemical Grade ≥98%; Pharmaceutical Intermediate Grade ≥99%; High-Purity Grade ≥99.5% |
| Molecular Formula | C6H3BrF2 |
| Molecular Weight | 177.00 |
| Appearance | Colorless to pale yellow transparent liquid |
| Packaging | 100 mL, 500 mL, or 1 L amber glass bottle; 25 kg fluorinated plastic drum or steel drum with protective liner for bulk packaging |
| Testing Indicators | Appearance — Visual inspection; Identification — FTIR and 1H NMR spectroscopy; Purity — GC-FID or GC-MS analysis; Water content — Karl Fischer titration (GB/T 6283); Density — ASTM D4052; Refractive index — ASTM D1218; Residual solvents — GC analysis according to ICH Q3C; Halogen content — Ion chromatography or elemental analysis; Impurities — GC-MS profiling. |
| Storage Notes | Store in a cool, dry, well-ventilated area away from direct sunlight and heat sources. Keep containers tightly sealed. Protect from moisture and incompatible substances. Store under inert gas atmosphere for long-term preservation. Avoid contact with strong oxidizing agents and strong bases. |
| Lead Time | 10 days |
1-Bromo-3,5-difluorobenzene is an aromatic halogenated intermediate widely used in organic synthesis. It serves as a building block for pharmaceutical intermediates, agrochemical intermediates, specialty chemicals, and materials research. The compound is commonly used in Suzuki coupling, nucleophilic aromatic substitution, and other cross-coupling reactions for the preparation of fluorinated aromatic compounds.