Methyl 2-(1-(aminomethyl)cyclohexyl)acetate
CAS: 138799-98-1
Category: Organic Intermediates
| Purity | Research Grade ≥95%, High-Purity Grade ≥98%, Pharmaceutical Intermediate Grade ≥99%, Reference Stand |
| Molecular Formula | C₁₀H₁₉NO₂ |
| Molecular Weight | 185.26 |
| Appearance | Colorless to pale yellow liquid or low-melting solid (depending on purity and temperature) |
| Packaging | 1g/5g/10g/25g/100g/glass bottle or aluminum foil bottle (for research); 1kg/5kg/25kg/plastic drum or PTFE-lined container (for intermediate synthesis) |
| Testing Indicators | Appearance — Visual inspection; Identification — NMR (¹H, ¹³C), FTIR, or GC-MS; Purity — GC-FID or HPLC (C18 column, UV detection for ester group); Assay — Titration (acid-base for amine content) or HPLC; Water content — Karl Fischer titration; Residual solvents — GC; Heavy metals — ICP-MS; Related impurities — GC or HPLC; Amine content — Perchloric acid titration in non-aqueous medium. |
| Storage Notes | Stored in a tightly sealed container in a cool, dry, well-ventilated area, protected from moisture, light, and air (CO₂ absorption may occur at the amine group); away from strong acids, strong oxidizers, and heat sources; store under inert atmosphere (nitrogen or argon) for long-term stability. |
| Lead Time | days |
Used as a key synthetic intermediate in the preparation of gabapentin (a gabapentinoid anticonvulsant drug) and its related analogs; as a building block for the synthesis of pharmaceutical compounds targeting the GABA system (e.g., voltage-gated calcium channel α₂δ subunit ligands); in medicinal chemistry research for the development of novel analgesics, anticonvulsants, and anxiolytics.